Thyrotoxic periodic paralysis (TPP) is a complication of thyrotoxicosis, more common amongst males in Asia. The underlying hyperthyroidism is often subtle causing difficulty in … Thyrotoxic periodic paralysis (TPP) is a rare complication of thyrotoxicosis and is classically associated with attacks of acute muscle weakness, thyrotoxic symptoms and hypokalemia (1,2).TPP has been reported more frequently in Asian males than in patients with other ancestral origins ().Even though hyperthyroidism is much more prevalent in women than in men, episodes of TPP are rare in women. It is characterized by sudden onset paralysis associated with hypokalemia. Definitive treatment of hyperthyroidism resolves TPP completely. Attacks may result from high levels of thyroid hormone. Introduction. Overview; Hypokalemic Periodic Paralysis (HypoKalemic) Normokalemic periodic paralysis (NormoKalemic) Hyperkalemic Periodic Paralysis (HyperKalemic) Thyrotoxic Periodic Paralysis (HypoKalemic) Related Diseases. Other triggers may include exercise, meals with a lot of carbohydrates, and stress. The condition primarily affects the lower extremities and is secondary to thyrotoxicosis. It has been increasingly reported in the USA due to the rise in the immigrant population. Thyrotoxic periodic paralysis is a rare complication of hyperthyroidism and is associated with hypokalemia and muscle paralysis. It occurs in people who have high levels of thyroid hormone in their blood (hyperthyroidism, thyrotoxicosis). Latest COVID-19 news; Medical; General Information; Diseases Overview. The underlying hyperthyroidism is often subtle causing difficulty in early diagnosis. Periodic paralysis is a group of rare genetic diseases that lead to weakness or paralysis from common triggers such as cold, heat, high carbohydrate meals, not eating, stress or excitement and physical activity of any kind. 2 We hereby report a male patient who … It causes sudden attacks of short-term muscle weakness, stiffness, or paralysis. Find a doctor; Suggest a Physician; Medical. ... Thyrotoxic PP. Thyroid-related problems are also usually present. Definition Thyrotoxic periodic paralysis (TPP) is a rare neurological disease … These episodes may be precipitated by heavy exercise, fasting, or high-carbohydrate meals. Many patients with TPP have no obvious symptoms related to hyperthyroidism. 1 Many affected patients do not have obvious symptoms and signs of hyperthyroidism and hence may be misdiagnosed or overlooked on presentation. This condition is most commonly seen in Asian men. Periodic Paralysis is a group of disorders whereby patients become weak due to triggers such as rest after exercise or certain foods.These disorders are part of a broader class of disorders called ion channelopathies, in which a genetic defect in a muscle ion channel results in symptoms of episodic stiffness or weakness in response to certain triggers. Thyrotoxic periodic paralysis Treatment consists of controlling thyrotoxicosis and beta-blocking agents. Thyrotoxic periodic paralysis (TPP), a disorder most commonly seen in Asian men, is characterized by abrupt onset of hypokalemia and paralysis.
Failure to recognize TPP may lead to improper management.
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